Acute Kidney Injury and Mortality in Patients with Rhabdomyolysis Due to Heat Stroke

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Jeremy Javier Hernandez
Fátima María Martínez González
Katya Lorena Wilhelmy Ledesma
Joaquin Córdova Erberk
Paola Alejandra Sterling Carrillo
Hiram Javier Jaramillo Ramirez M.D

Abstract

Introduction: Heat stroke is a well-known condition among people who live in high climate temperatures. In the city of Mexicali, temperatures above 40° C (104° F) are common during summer time, with constant admissions to the emergency room due to classic heat stroke. Hypotension, polypnea, anuria, coma, respiratory failure and kidney failure, were related to a higher mortality rate.


Methods: This is a prospective observational cohort study of patients during the period of June to August 2018, with heat stroke defined as a central body temperature of 40°c or higher, cognitive impairment and recent exposure to high temperatures, admitted to the Emergency Room of the General Hospital of Mexicali. At arrival, a full medical history was taken and laboratory tests were obtained.


Results: twenty-eight patients were admitted with the confirmed diagnosis of classical heat stroke, with a rectal temperature between 40 to 42.2°C. Of these patients, 13 developed rhabdomyolysis, with CPK levels ranging from 1030 U/l to 18977 U/l. From these 13 patients with rhabdomyolysis, 12 developed AKI (p=0.003). Mortality in the group of patients who developed rhabdomyolysis was greater than those who did not develop rhabdomyolysis.


Conclusion: The development of Rhabdomyolysis is a high-risk factor for acute kidney injury and death.

Article Details

How to Cite
Jeremy Javier Hernandez, Fátima María Martínez González, Katya Lorena Wilhelmy Ledesma, Joaquin Córdova Erberk, Paola Alejandra Sterling Carrillo, & Hiram Javier Jaramillo Ramirez M.D. (2021). Acute Kidney Injury and Mortality in Patients with Rhabdomyolysis Due to Heat Stroke. International Journal of Medical Science and Clinical Research Studies, 1(6), 147–150. Retrieved from https://ijmscr.ijpbms.com/index.php/ijmscrs/article/view/47
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